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Dihexa
Also known as: N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide
Research / Investigational
Dihexa is an orally active small peptide derivative of angiotensin IV investigated for its ability to promote synapse formation.
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Overview
Dihexa is an orally active small peptide derivative of angiotensin IV investigated for its ability to promote synapse formation.
FDA Approval Status
Not approved by the FDA. Investigational or intended for research purposes only.
Mechanism of Action
Potentiates hepatocyte growth factor (HGF)/c-Met signaling to promote synaptogenesis.
Current Research
Preclinical rodent studies suggest improved learning and memory; no human trials.
Research strength: Preliminary
Potential Medical Uses
- Investigational only
Potential Benefits
- Increased dendritic spine density (animals)
- Potential nootropic effects
Known Side Effects
- Unknown long-term human safety
- Theoretical tumorigenic risk via HGF
Contraindications
- Active malignancy (theoretical)
- Pregnancy
Drug Interactions
- Not well characterized
Administration Methods
- Oral (research)
- Transdermal (research)
Half-life
Hours (estimated)
Reconstitution
Solvent varies by protocol.
Storage & Handling
Refrigerated; protect from light.
References & Sources
Frequently Asked Questions
Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.