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Follistatin-344
Also known as: FST-344
Research / Investigational
Follistatin-344 is a 344-amino-acid isoform of the endogenous myostatin/activin inhibitor follistatin, investigated for muscle growth and muscular dystrophies.
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Overview
Follistatin-344 is a 344-amino-acid isoform of the endogenous myostatin/activin inhibitor follistatin, investigated for muscle growth and muscular dystrophies.
FDA Approval Status
Not approved by the FDA. Investigational or intended for research purposes only.
Mechanism of Action
Binds and neutralizes myostatin and activin, disinhibiting muscle protein synthesis.
Current Research
Gene-therapy trials for Duchenne and Becker muscular dystrophy; peptide/protein form remains investigational.
Research strength: Preliminary
Potential Medical Uses
- Investigational only
Potential Benefits
- Increased muscle mass in preclinical models
Known Side Effects
- Injection-site reactions
- Long-term human safety unknown
Contraindications
- Pregnancy
- Active malignancy
Drug Interactions
- Anabolic agents (theoretical)
Administration Methods
- Subcutaneous or intramuscular injection (research)
Half-life
Hours to days depending on isoform
Reconstitution
Bacteriostatic water.
Storage & Handling
Refrigerated reconstituted; frozen long-term.
References & Sources
Frequently Asked Questions
Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.