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★ = FDA-approved medical indication•
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Evidence-based · Educational only•
36+ Peptides indexed•
Free research library•
Free newsletter — subscribe below•
★ = FDA-approved medical indication•
Not medical advice — always consult a clinician•
Peptide Knowledge Center
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Glucagon

FDA-Approved

Glucagon is a 29-amino-acid peptide used to reverse severe hypoglycemia.

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Overview

Glucagon is a 29-amino-acid peptide used to reverse severe hypoglycemia.

FDA Approval Status

Approved by the FDA for at least one medical indication (see approved uses below).

Mechanism of Action

Activates hepatic glucagon receptors to stimulate glycogenolysis and gluconeogenesis.

Current Research

Well-established.
Research strength: Strong

Potential Medical Uses

  • Severe hypoglycemia rescue
  • Diagnostic use in GI imaging

Potential Benefits

  • Rapid glucose elevation

Known Side Effects

  • Nausea
  • Vomiting

Contraindications

  • Pheochromocytoma
  • Insulinoma

Drug Interactions

  • Anticoagulants (may potentiate warfarin)

Administration Methods

  • Intramuscular
  • Subcutaneous
  • Intranasal (Baqsimi)

Half-life

~3–6 minutes

Reconstitution

Emergency kits are self-contained.

Storage & Handling

Room temperature (device-dependent).

References & Sources

Frequently Asked Questions

Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.