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Goserelin
Also known as: Zoladex
FDA-Approved
Goserelin is a GnRH agonist delivered as a subcutaneous implant used in hormone-sensitive cancers and endometriosis.
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Overview
Goserelin is a GnRH agonist delivered as a subcutaneous implant used in hormone-sensitive cancers and endometriosis.
FDA Approval Status
Approved by the FDA for at least one medical indication (see approved uses below).
Mechanism of Action
Continuous GnRH agonism suppresses LH/FSH.
Current Research
Established.
Research strength: Strong
Potential Medical Uses
- Prostate cancer
- Breast cancer (premenopausal)
- Endometriosis
Potential Benefits
- Long dosing interval
Known Side Effects
- Hot flashes
- Bone density loss
Contraindications
- Pregnancy
Drug Interactions
- QT-prolonging drugs
Administration Methods
- Subcutaneous implant every 1 or 3 months
Half-life
~4 hours
Reconstitution
Prefilled implant.
Storage & Handling
Room temperature.
References & Sources
Frequently Asked Questions
Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.