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Human Chorionic Gonadotropin
Also known as: hCG / Pregnyl / Novarel
FDA-Approved
Human chorionic gonadotropin is a placental glycopeptide with LH-like activity, approved for ovulation induction, assisted reproduction trigger, and select male hypogonadism/cryptorchidism indications.
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Overview
Human chorionic gonadotropin is a placental glycopeptide with LH-like activity, approved for ovulation induction, assisted reproduction trigger, and select male hypogonadism/cryptorchidism indications.
FDA Approval Status
Approved by the FDA for at least one medical indication (see approved uses below).
Mechanism of Action
Binds LH receptors to stimulate ovulation, corpus luteum progesterone, and Leydig-cell testosterone production.
Current Research
Long-established clinical use.
Research strength: Strong
Potential Medical Uses
- Ovulation induction
- IVF ovulation trigger
- Prepubertal cryptorchidism
- Hypogonadotropic hypogonadism
Potential Benefits
- Preserves testicular function during TRT
- Supports fertility protocols
Known Side Effects
- Injection-site reactions
- Headache
- OHSS (in women)
- Gynecomastia (in men)
Contraindications
- Precocious puberty
- Hormone-dependent tumors
Drug Interactions
- May confound pregnancy tests
Administration Methods
- Subcutaneous or intramuscular injection
Half-life
~24–36 hours
Reconstitution
Kit includes diluent.
Storage & Handling
Refrigerate reconstituted; use within 30–60 days per label.
References & Sources
Frequently Asked Questions
Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.