Evidence-based · Educational only
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★ = FDA-approved medical indication
Not medical advice — always consult a clinician
Evidence-based · Educational only
36+ Peptides indexed
Free research library
Free newsletter — subscribe below
★ = FDA-approved medical indication
Not medical advice — always consult a clinician
All peptides

Ipamorelin

Research / Investigational

Ipamorelin is a pentapeptide growth hormone secretagogue with minimal effect on cortisol or prolactin.

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Overview

Ipamorelin is a pentapeptide growth hormone secretagogue with minimal effect on cortisol or prolactin.

FDA Approval Status

Not approved by the FDA. Investigational or intended for research purposes only.

Mechanism of Action

Selective agonist of the ghrelin/GHS-R1a receptor on pituitary somatotrophs.

Current Research

Small human studies show pulsatile GH release; not approved for clinical use.
Research strength: Moderate

Potential Medical Uses

  • Investigational only

Potential Benefits

  • Selective GH release
  • Minimal cortisol elevation compared with other secretagogues

Known Side Effects

  • Headache
  • Injection-site reactions
  • Transient flushing

Contraindications

  • Active malignancy
  • Pregnancy

Drug Interactions

  • Somatostatin analogs may blunt effects

Administration Methods

  • Subcutaneous injection

Half-life

~2 hours

Reconstitution

Bacteriostatic water, typically 1–2 mL per vial.

Storage & Handling

Refrigerate reconstituted vial; use within 30 days.

References & Sources

Frequently Asked Questions

Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.