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KPV
Also known as: Lysine-Proline-Valine
Research / Investigational
KPV is the C-terminal Lys-Pro-Val fragment of α-melanocyte-stimulating hormone. It has been investigated as a topical and systemic anti-inflammatory in models of colitis, dermatitis, and wound healing.
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Overview
KPV is the C-terminal Lys-Pro-Val fragment of α-melanocyte-stimulating hormone. It has been investigated as a topical and systemic anti-inflammatory in models of colitis, dermatitis, and wound healing.
FDA Approval Status
Not approved by the FDA. Investigational or intended for research purposes only.
Mechanism of Action
Modulates NF-κB signaling and pro-inflammatory cytokine release without engaging melanocortin receptors.
Current Research
Preclinical studies in colitis, wound healing, and dermatologic inflammation.
Research strength: Preliminary
Potential Medical Uses
- Investigational only
Potential Benefits
- Reduced inflammatory cytokines in models
Known Side Effects
- Not well characterized in humans
Contraindications
- Pregnancy
- Known hypersensitivity
Drug Interactions
- Immunosuppressants (theoretical)
Administration Methods
- Oral, topical, or subcutaneous (research)
Half-life
Short (minutes to hours)
Reconstitution
Bacteriostatic water for injectable forms.
Storage & Handling
Refrigerate reconstituted.
References & Sources
Frequently Asked Questions
Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.