Evidence-based · Educational only
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★ = FDA-approved medical indication
Not medical advice — always consult a clinician
Evidence-based · Educational only
36+ Peptides indexed
Free research library
Free newsletter — subscribe below
★ = FDA-approved medical indication
Not medical advice — always consult a clinician
All peptides

L-Glutathione

Also known as: GSH
Research / Investigational

Glutathione is a naturally occurring tripeptide (glutamate-cysteine-glycine) and the body's primary intracellular antioxidant.

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Overview

Glutathione is a naturally occurring tripeptide (glutamate-cysteine-glycine) and the body's primary intracellular antioxidant.

FDA Approval Status

Not approved by the FDA. Investigational or intended for research purposes only.

Mechanism of Action

Neutralizes reactive oxygen species and supports phase-II detoxification pathways.

Current Research

Small trials suggest benefit in oxidative-stress conditions; broad clinical outcome data limited.
Research strength: Moderate

Potential Medical Uses

  • Adjunct in acetaminophen toxicity (as N-acetylcysteine precursor)

Potential Benefits

  • Antioxidant activity
  • Detox pathway support
  • Skin research applications

Known Side Effects

  • Injection-site reactions
  • GI upset (oral)

Contraindications

  • Known hypersensitivity

Drug Interactions

  • Chemotherapeutics (theoretical)

Administration Methods

  • Intravenous
  • Subcutaneous
  • Oral (poor bioavailability)

Half-life

Minutes (systemic)

Reconstitution

Sterile water or bacteriostatic water.

Storage & Handling

Refrigerated; protect from light.

References & Sources

Frequently Asked Questions

Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.