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★ = FDA-approved medical indication
Not medical advice — always consult a clinician
Evidence-based · Educational only
36+ Peptides indexed
Free research library
Free newsletter — subscribe below
★ = FDA-approved medical indication
Not medical advice — always consult a clinician
All peptides

NAD+

Also known as: Nicotinamide Adenine Dinucleotide
Research / Investigational

NAD+ is an essential coenzyme found in every living cell, involved in redox reactions, DNA repair, and sirtuin activity.

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Overview

NAD+ is an essential coenzyme found in every living cell, involved in redox reactions, DNA repair, and sirtuin activity.

FDA Approval Status

Not approved by the FDA. Investigational or intended for research purposes only.

Mechanism of Action

Serves as an electron carrier and substrate for sirtuins, PARPs, and CD38.

Current Research

Preclinical data supports mitochondrial and aging benefits; human trials ongoing.
Research strength: Moderate

Potential Medical Uses

  • Not FDA-approved for anti-aging

Potential Benefits

  • Supports mitochondrial function
  • May support DNA repair

Known Side Effects

  • Flushing during IV
  • Nausea
  • Injection-site reactions

Contraindications

  • Known hypersensitivity

Drug Interactions

  • Not well characterized

Administration Methods

  • Intravenous
  • Subcutaneous
  • Oral precursors (NR/NMN)

Half-life

Short in circulation; intracellular pools persist

Reconstitution

Sterile water.

Storage & Handling

Refrigerated; protect from light.

References & Sources

Frequently Asked Questions

Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.