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Evidence-based · Educational only•
36+ Peptides indexed•
Free research library•
Free newsletter — subscribe below•
★ = FDA-approved medical indication•
Not medical advice — always consult a clinician•
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Sermorelin

FDA-Approved

Sermorelin is a GHRH(1-29) analog that stimulates endogenous GH release; it received FDA approval for diagnostic and pediatric use (product later discontinued commercially).

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Overview

Sermorelin is a GHRH(1-29) analog that stimulates endogenous GH release; it received FDA approval for diagnostic and pediatric use (product later discontinued commercially).

FDA Approval Status

Approved by the FDA for at least one medical indication (see approved uses below).

Mechanism of Action

GHRH receptor agonism at the pituitary.

Current Research

Older approval; still used off-label.
Research strength: Moderate

Potential Medical Uses

  • Historical: pediatric GHD; diagnostic testing

Potential Benefits

  • Stimulates natural GH pulses

Known Side Effects

  • Injection-site reactions
  • Flushing

Contraindications

  • Active malignancy
  • Pregnancy

Drug Interactions

  • Glucocorticoids

Administration Methods

  • Subcutaneous injection

Half-life

~10–20 minutes

Reconstitution

Bacteriostatic water.

Storage & Handling

Refrigerate.

References & Sources

Frequently Asked Questions

Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.