Teriparatide

Also known as: Forteo

FDA-Approved

Teriparatide is a recombinant fragment of parathyroid hormone used for osteoporosis at high fracture risk.

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Overview

Teriparatide is a recombinant fragment of parathyroid hormone used for osteoporosis at high fracture risk.

FDA Approval Status

Approved by the FDA for at least one medical indication (see approved uses below).

Mechanism of Action

Intermittent PTH receptor activation stimulates osteoblastic bone formation.

Current Research

Fracture-reduction trials.

Research strength: Strong

Potential Medical Uses

Postmenopausal osteoporosis
Male osteoporosis
Glucocorticoid-induced osteoporosis

Potential Benefits

Increases bone mineral density
Reduces fracture risk

Known Side Effects

Nausea
Dizziness
Hypercalcemia

Contraindications

Prior skeletal radiation
Paget disease
Elevated baseline calcium

Drug Interactions

Digoxin (monitor calcium)

Administration Methods

Subcutaneous injection daily

Half-life

~1 hour

Reconstitution

Prefilled pen.

Storage & Handling

Refrigerate.

References & Sources

FDA label

Frequently Asked Questions

Information on this page is educational and general in nature. It is not medical advice. Consult a qualified healthcare professional before making any medical decisions.